Iron and zinc status Of anemic adolescent girls before and after iron and zinc supplementation
Yustina Anie Indriastuti Kurniawan
ABSTRACT Nutrition in adolescent has not received adequate attention. Aside from anemia due to iron deficiency, chronic malnutrition and other micronutrient deficiencies such as zinc deficiency may also affect adolescent girls. Double blind, community trial was carried out to investigate whether iron-zinc supplementation would improve iron and zinc status among anemic adolescent girls 10�12 years old. Subjects (n=133) with hemoglobin concentration <120 g/L were randomized to receive 60 mg iron (iron group), or 30 mg iron and 15 mg zinc (iron/zinc 2:1 group), or 60 mg iron and 15 mg zinc (iron/zinc 4:1 group) for 12 weeks daily supplementation. Hemoglobin, serum ferritin, serum transferrin receptor, zinc protophorphyrin and serum zinc were determined for the iron and zinc status. Supplementation with iron or with iron and zinc significantly improved iron and zinc status. The changes of hemoglobin were 9.6 g/L in iron group, 6.6 g/L in iron/zinc 2:1 group and 3.4 g/L in iron/zinc 4:1 group. The changes of serum zinc were 2.7 mmol/L in iron group, 4.1 mmol/L in iron/zinc 2:1 group and 3.5 mmol/L in iron/zinc 4:1 group. In iron/zinc 2:1 group, no one subjects suffered from iron deficiency anemia and zinc deficiency by the end of supplementation. It was concluded that iron supplementation alone improved iron and zinc status effectively, adding zinc protected the adverse effect of iron on decreasing zinc absorption. Therefore, it is timely to establish ironzinc supplementation program targeted to adolescent girls.
- No. Panggil 610.4 ANI i
- Edisi
- Pengarang Yustina Anie Indriastuti Kurniawan
- Penerbit
